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The BBB disruption, indicated by microhemorrhages [26], allows the entry of fibrinogen, plasma proteins, RBC, and other toxic substances into the brain parenchyma, further damaging neurons [233]

mansoni TGR was here shown to possess substantial TrxR, GR, and Grx activity, with rates comparable to those reported for native TGR purified from mouse testis [26] and more than 40-fold more active than recombinant mouse TGR [48]

Moreover, these drugs can improve cholesterol, blood pressure, and overall heart health

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The regulatory landscape is evolving rapidly