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Common adverse effects include gastrointestinal symptoms, which affect the majority of patients to varying degrees: Nausea (20-44% of patients) usually most pronounced during dose escalation Diarrhea (20-30%) Constipation (15-24%) Vomiting (9-24%) Abdominal pain (6-10%) These symptoms typically diminish over time as physiological adaptation occurs

Mothers considering semaglutide for weight loss face an important decision: the medication is not recommended during breastfeeding because animal studies show it enters breast milk and may affect infant development

10.1016/j.jphs.2021.09.008 40 DaherB.ParksS