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Increased Nausea + GI Side Effects GLP-1s already cause: nausea reflux delayed stomach emptying bloating Wine and other alcohols can worsen: gastric irritation reflux vomiting stomach discomfort This is why many users naturally stop drinking (that's a GOOD THING

Now on to taste, I had heard pyruvate tasted bad, but there is something intensely disturbing about knowing something will be bad, then smelling it and it smelling distinctly like maple syrup

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Fourth, some inclusion criteria may cause selection bias

A standard-dose semaglutide or tirzepatide protocol may be a better fit if your primary goal is significant weight loss, you have a higher starting BMI, you struggle with strong appetite or food noise, you want more noticeable appetite suppression, or you have previously tolerated GLP-1 medications well