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Those suffering from a rare inherited disorder called maple syrup urine disease, have a faulty enzyme in the degradation pathway common to isoleucine, leucine, and valine

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Corroborating, Lucas and colleagues showed that the risk of depression in adult women decreases with increasing consumption of caffeinated coffee, but not with decaffeinated coffee [105]

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2.16 Xanthine oxidase (XO) The XO activity was measured spectrophotometrically by the formation of uric acid by the xanthine through the increase of absorbance recorded at 290 nm