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In addition, we performed site-directed mutagenesis and biochemical analysis based on the structural information, which revealed that the Cys20 and Lys8 residues are important for enzymatic activity

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In addition, increased expression of TGF also reduces expression of Notch ligand and receptor in aged skeletal muscle and contributes to loss of muscle mass and function with aging[30]

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This concept, known as chrononutrition, explores how meal timing, frequency, and fasting periods influence our bodys biological rhythms and organ function [63]