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There now exist multiple studies (see this analysis of multiple studies on acetaminophen use during pregnancy) illustrating a potential causal link between higher rates of autism and acetaminophen use during pregnancy

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Muscle Relaxants Hydrocodone bitartrate and acetaminophen tablets may enhance the neuromuscular blocking action of skeletal muscle relaxants and produce an increased degree of respiratory depression

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Similar findings, however, have been observed in normal or well-compensated patients with heart failure with agents possessing significant negative inotropic effects