The Endocrine Society's position statement on obesity pharmacotherapy describes weight regain after stopping medication as evidence of ongoing disease activity, not treatment failure
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Citations Zini, A., & Al-Hathal, N
You've tried physical therapy, anti-inflammatories, elimination diets, and rest
GLP-1s combined effects help promote satiety, and include: Slowing gastric emptying Decreasing food cravings and desire for alcohol Improving blood sugar control, especially for people with type-2 diabetes Reducing appetite What Foods Help Increase the GLP-1 Hormone