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The effect of DSePA administration on RP was studied by subjecting mice to thoracic irradiation (X- or -rays, 18 Gy), treating them with DSePA (2.5 mg/kg body weight for three time a week for 6 months beginning on the day of irradiation) during the post-irradiation period and monitoring the incidence of RP through immunohistochemical and CT analysis (Table 2) [61, 62]

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This strategy not only maximizes the therapeutic potential of each cytokine but also offers a versatile approach to incorporating gene delivery and recombinant cytokines as tools to enhance anti-cancer treatment efficacy