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GHK-Cu, or Glycyl-L-Histidyl-L-Lysine-Copper, is a naturally occurring copper peptide that has garnered significant attention in the fields of dermatology and regenerative medicine

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In vitro and in vivo models, it was found that in the IDH1 mutant glioma cells intervened by triptolide, the transcriptional activity of Nrf2 was suppressed, and the expressions of GCLC, GCLM and SLC7A11 were down-regulated, thereby disrupting the metabolism of glutathione

Replenishing and maintaining glutathione levels through supplementation, they suggest, could therefore provide therapeutic benefit in Parkinsons disease patients

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