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Clinical trials of GLP-1 medications have consistently demonstrated that whilst participants lose considerable weight, a proportion of this weight loss includes lean body mass

The gradual onset allows the body to adapt to the medication whilst minimising adverse effects, particularly gastrointestinal symptoms that can occur with rapid dose escalation

and for adults with overweight in the presence of at least one weight-related health condition like high blood pressure or heart disease

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GLP-1 medications work by binding to receptors that control hunger signals and glucose metabolism, creating a more comprehensive metabolic effect than phentermine alone