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Among the patients who develop NASH, 1020% will progress to higher-grade fibrosis and approximately 5% will develop overt cirrhosis (1) ( Figure 1 Triglycerides (TG) accumulation is likely one of the first steps in the pathophysiology of NAFLD as a result of an impaired free fatty acid (FFA) metabolism in the liver (Figure 2)

adults now reporting having used a GLP-1 medication for weight loss, diabetes, or both, hair loss has moved from an anecdotal complaint to a formally studied adverse event

Athauda and colleagues 26 reported that exenatide 2 mg once weekly had numerically greater improvements in individual domains assessing mood/depression across all observer rated outcome measures including the mood/apathy domain of the Non-Motor Symptoms Scale in Parkinson Disease

2 Apolzan, J.W., LaRose, J.G., Anton, S.D

Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and European Association for the Study of Diabetes