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In the intervention arm the HbA1c at 6 months was on average 42.5 mmol/mol, whereas in placebo was 52.0 mmol/mol

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The concentrations of Exe4 and other hepatic markers in plasma were assessed using commercially available assay kits (Exe4: Abcam, AST and ALT: Sigma-Aldrich, Albumin: Fuji Rebis) following the manufacturers protocols, and the absorbance of each sample was measured using a plate reader