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These include glucocorticoid receptor genes, FK506 binding protein 5 and spindle, centromere-associated complex 2, oxytocin receptor, oligodendrocyte genes and BDNF, among ohters 130,131

One issue is the chemical instability of active compounds such as curcumin and aloin, which degrade rapidly in gastric conditions unless protected by encapsulation or phytosomal systems

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