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Bench to bedside progress will depend on integrative multidisciplinary approaches between basic scientists and clinical investigators to reveal the pathological mechanism of autism
Oxidative stress occurs when there is an imbalance between excessive reactive oxygen species (ROS) production and/or diminished cellular antioxidant defenses
Computational analysisscRNA data processing and reconstruction of context-specific metabolic models Prior to the reconstruction of single-cell metabolic models, scRNA datasets (Methods: scRNA Datasets) were downloaded from NCBIs Gene Expression Omnibus 89 for pre-processing with Seurat 90 and StanDep 20
extrapolation to human physiological outcomes has not been established through controlled human trials
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