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AFB1, a hepatotoxic compound, is known to induce the expression of autophagy-related protein P62, which has been implicated in developing liver and breast cancer [18, 19]

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A letter to the editor to the Lin et al study noted the different definitions of DR progression used as the primary outcome between their study and the original CVOT studies

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Efficacy and safety of retatrutide, a novel GLP-1, GIP, and glucagon receptor agonist for obesity treatment: a systematic review and meta-analysis of randomized controlled trials