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It is the body's main timekeeper

Through the website JASPAR ( we observed that, among the peaks near the TSS in GCLC, a sequence was highly homologous to the NRF2-binding motif (Fig

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In our study, the AEDG peptide was most likely to interact with the linker histones H1/6, as requiring the lowest binding energy (sequence Tyr-Arg-Lys-Thr-Gln, binding energy 64.51 kcal/mol) and H1/3 (sequence His-Pro-Ser-Tyr-Met-Ala-His-Pro-Ala-Arg-Lys, binding energy 56.49 kcal/mol)