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Free Radic Res 2000
An oral acute toxicity study of GSH in mice found that the lethal dose 50 (LD50) was more than 5 g/kg, indicating that glutathione is nontoxic
The physical and mental chaos of the early titration phase gives way to a new normal that feels sustainable rather than forced
However, several proposed actions are believed to underlie its physiological effects: 1
The compound was developed by Peter de Keizer and colleagues at Erasmus University Medical Center (Rotterdam) and published in a landmark 2017 Cell paper (Baar et al., Cell 169:132-147) demonstrating selective induction of apoptosis in cellular senescence research models
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