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Tissues were then collected and fixed for 24 h in 4% PFA in PBS at room temperature and then transferred to 70% ethanol

Ozempic vs Bydureon (Exenatide ER) The Sustain 3 study compared the treatment outcomes of Ozempic with Bydureon (Exenatide ER)

Key points: Leverage platform data from similar biologics Eliminate redundant toxicology studies Combine endpoints within the same study Use in vitro and computational models earlier Align with the 3Rs principle (Replacement, Reduction, Refinement) Important step toward more ethical and efficient ocular drug development

The body adapts