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As a transcription target of p53, the activity of spermidine/spermine N 1 -acetyltransferase 1 (SAT1), the rate-limiting enzyme in polyamine catabolism, induces lipid peroxidation and sensitizes cells to undergo ferroptosis and the deletion of SAT1 suppresses p53 and p53 3 KR -mediated ferroptosis

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She is the founder of The Pause Life, the bestselling author of The Galveston Diet and The New Menopause, and host of the podcast unPAUSED