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Early improvements in skin hydration, radiance, and tone can appear within 34 weeks

Treatment availability varies by state

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12-16 Conversely, certain types of gut microbial dysbiosis can dampen gut motility, establishing a bidirectional relationship between the gut microbiota and gut transit time

When combined with medications such as sodium-glucose cotransporter-2 (SGLT-2) inhibitors or specific insulin formulations that exhibit complementary effects on weight regulation, combination therapy has the potential to significantly enhance weight loss outcomes and improve body composition in patients with co-morbid type 2 diabetes and obesity