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Findings Participants and Intervention: Between October 5, 2018, and February 1, 2019, 304 individuals were randomly assigned to either receive semaglutide 2.4 mg (n = 152) or placebo (n = 152) and were encompassed in the comprehensive analysis set (comprising all randomized individuals as per the intention-to-treat principle)

Zepbound carries a brand premium and limited generic competition post-FDA approval

However, with seven additional Phase 3 trials expected to wrap up in 2026, experts believe it could soon become a major option for people with significant weight loss needsespecially those managing obesity-related joint pain

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