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The TRIUMPH-1 Phase 3 clinical trial results, announced in May 2026, showcased participants losing up to 28.3% of their body weight over 80 weeks, indicating significant promise compared to other options like tirzepatide (Zepbound) and semaglutide (Wegovy)

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While some nausea and constipation may still be present, the intensity typically begins declining as your stomach and intestinal lining become desensitized to the medication

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