It is studied in oxidative stress models, redox biology, drug detoxification (Phase II conjugation), and as a substrate for glutathione peroxidase and S-transferase research
10.1039/c9mt00186g
MEDI7247 has shown remarkable antitumor activity in hematological malignancies such as AML, MM, diffuse large B cell lymphoma (DLBCL), acute lymphoblastic leukemia (ALL), Burkitt lymphoma, as well as solid tumors including colorectal cancer, small cell lung cancer, and head and neck squamous cell carcinoma (Pore et al., 2018
Complications Complications were infrequent and distributed similarly between groups
Research perspective A 2001 editorial in the European Journal of Anaesthesiology described DSIP as "incredibly safe" based on the lack of lethal doses in animal studies and absence of significant side effects in human trials beyond transient symptoms