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As the field develops, direct measurement of circulating MOTS-c may become a useful biomarker for guiding dose adjustments, similar to how IGF-1 is used to monitor growth hormone or testosterone levels guide TRT dosing

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Additionally, a lower platelet cytochrome c oxidase activity is associated with sepsis mortality [65] (that frequently take place in the presence of cardiac dysfunction)

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Symptoms include arrhythmias, feeding difficulties, hypotonia, lethargy, hypoketotic hypoglycaemia, elevated liver enzymes, and rhabdomyolysis or hepatomegaly, among other conditions [8284]