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2 IV Acetadote protects liver cells in 2 ways: It helps replenish glutathione It binds to and removes NAPQI Return to top The maximum adult therapeutic dose of acetaminophen is 4 grams/24 hours 3 The maximum dose for children less than 12 years is 75 mg/kg 4 Acute overdose is defined as ingestion of 150 mg/kg or 12 grams/24 hours 4 Four stages of acetaminophen overdose 5 Return to top When time is liver, timing is critical Treatment Recommendations The following recommendations are related to acute acetaminophen ingestion
Affermazioni comprovate dall'EFSA (Autorit europea per la sicurezza alimentare)
(Malayala et al, 2022)
Close monitoring of both milk supply and infant growth is essential, and documented informed consent about potential risks and benefits should be obtained before starting treatment
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