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MITF is thought to act as a master regulator of melanogenesis, supporting the transcription of multiple enzymes essential to melanin synthesis, notably tyrosinase, tyrosinase-related protein 1 (TRP1), and dopachrome tautomerase (DCT or TRP2)

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The role of the gut microbiota in the pathogenesis of diabetes

gattii , Aspergillus fumigatus , and Candida albicans , even in CD4 + T cell-deficient hosts, supporting their potential as a broad-spectrum vaccine (Wang et al., 2019)

Specifically, strategies targeting CSC metabolism have gained attention, as CSCs exhibit unique metabolic dependencies that distinguish them from non-stem cancer cells