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IQAir's 2025 World Air Quality Report placed India's average PM2.5 level at roughly 48.9 g/m nearly ten times the WHO's annual guideline and air pollution is a well-documented driver of oxidative stress

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Secondly, the combination of different functional nanoagents may cause corresponding toxic side effects to the human body, thus the biodegradability, stability, and safety of nanomedicines still need further validation