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Biochemical properties of recombinant prolyl dipeptidases DPP-IV and DPP8

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Under physiological conditions, the cytoplasmic protein Kelch-like ECH-associated protein 1 (Keap1), an adapter protein of Cullin-3-based ubiquitin ligase, binds to NRF2 to suppress NRF2 activation by mediating its ubiquitination and degradation (Fig

Alternatively, serine can be converted to glycine for glutathione synthesis [48,49]