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A: Some people notice changes in appetite or glucose readings within the first few weeks

This could also disrupt your metabolic adaptation of the medication, making it harder to achieve long-term results. If you stop using semaglutide for a period of time, most or all of the weight you lost could return, and weight loss might be more challenging when you resume the medication

The established trust and proven effectiveness of these injectable forms, particularly for the treatment of type 2 diabetes and obesity, have solidified this segment's leading position

Theyre usually temporary, though, and resolve on their own in a few minutes

In February 2025, the FDA declared that Novo Nordisk had increased manufacturing capabilities enough to keep up with demand, and the shortage was over