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1,2 Skin type: II Skin type: III Skin type: III Skin type: IV Study Design The safety and efficacy of Tri-Luma Cream were evaluated for the treatment of moderate to severe facial melasma in two phase 3, multicenter, randomized, investigator-blind, active-control, parallel-group trials, which were identical in design

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CMO 10 Rule 502(d): This order establishes rules regarding the production and disclosure of certain materials that may involve claims of privilege or work product protections