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Its enhanced binding protein resistance and extended stability enable controlled concentration-response studies with reduced experimental variability

The weight loss achievedoften exceeding 15% of body weightcan reverse many of the markers of metabolic syndrome, such as high triglycerides and elevated blood pressure

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Moreover, because GLP-1R is expressed throughout the body, stimulation with a GLP-1R agonist or indirectly with a DPP-IV inhibitor can have a broad systemic effect on systemic metabolism, which, in turn, ameliorates peripheral and central insulin resistance in AD and MD (Athauda and Foltynie, 2016)