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We are thankful to the Integrated Islet Distribution Program (IIDP) funded by the National Institutes of Diabetes and Digestive and Kidney Disease (NIDDK) and with support from the Juvenile Diabetes Research Foundation International (JDRFI) for providing human islets

Alterations in Cholinergic Pathways and Therapeutic Strategies Targeting Cholinergic System after Traumatic Brain Injury

Hawkins David L

This seemingly minor modification creates profound pharmacological differences from both native IGF-1 and IGF-1 LR3

Sustained intracellular growth signaling environment: Because of its extended activity and direct receptor binding, IGF-1 LR3 creates a more persistent intracellular growth signal in experimental systems