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Thank you, Mark, Mrs

Study inclusion criteria were (1) original clinical studies reporting in vivo GSH levels in the brain, serum, plasma, or blood cells (2)

If you dive in to the validation data a little bit, even though the headline is it predicts diarrhea, that isn't the full story there

Although the mechanisms by which these reagents modulate GPx1 expression are not clear, it has been shown that GPx1 can be upregulated by activation of the peroxisome proliferator-activated receptor--coactivator-1a (PGC1) pathway, possibly via the subsequent activation of Nrf2 [161]

Oxidative stress is an imbalance between free radicals (unstable molecules that can cause damage) and the antioxidants that neutralize them