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The treatment has substantial clinical trial support for various musculoskeletal conditions

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It also bumps up against the mechanism of action of GLP-1s, which are approved by the FDA for long-term weight management because their discontinuation can lead to weight regain

Compounds such as EGCG and apigenin promote apoptosis in melanoma cells by modulating pathways like MAPK and PI3K-AKT, while green tea polyphenols inhibit histone deacetylase (HDAC) and activate histone acetyltransferase (HAT), reactivating tumor-suppressor genes silenced during melanoma progression 138,148