Wegovy and Ozempic activate the GLP-1 pathway, while Zepbound and Mounjaro activate two: both GLP-1 and GIP
Head Neck 37:727734 Mimura J, Inose-Maruyama A, Taniuchi S, Kosaka K, Yoshida H, Yamazaki H, Kasai S, Harada N, Kaufman RJ, Oyadomari S, Itoh K (2019) Concomitant Nrf2- and ATF4-activation by carnosic acid cooperatively induces expression of cytoprotective genes
GSH Deficiency and OxS in Aging GSH synthesis occurs in two steps, catalyzed by the enzymes glutamate cysteine ligase (GCL, comprised of catalytic and modifier subunits GCLC and GCLM), and GSS, to form the tripeptide glutathione (-glutamyl-cysteinyl-glycine) (22,23)
This isn't a reason to fear the medication: it's a reason to be intentional
The authors are indebted to the trial participants, the investigators and trial site staff who conducted the trial