Consequently, multiple PPP enzymes have been identified as promising therapeutic targets, functioning dually as metabolic catalysts and regulators of diverse cellular processes, positioning them as strategic targets for anticancer drug development [36]

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The lysine at position 26 is then derivatized through a bifunctional linker composed of two gamma-glutamic acid spacers and a short polyethylene-glycol (mini-PEG) segment, terminating in a C18 fatty diacid moiety [1]
The indication is that not only are the number of receptors available in the membrane modified in this model, but also that their composition is altered