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5-Amino-1MQ's 35% visceral fat reduction in mice is impressive for a murine model, but human translation typically sees 3050% attenuation of effect size
This differential inhibition profile suggests a flexible binding mechanism, particularly for the dimer, which may selectively modulate GSTP1 activity depending on substrate concentration
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Peptides are made from amino acids, which are the building blocks of proteins, and many peptides act as messengers that help regulate functions such as metabolism, tissue repair, hormone signaling, immune response, sleep, and appetite
Ethics declarations COMPETING INTERESTS The authors declare no competing interests
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