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Histochemistry 89 , 151161 (1988)

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And the data collection tools used in trials, like standardized questionnaires and adverse event checklists, may not capture the full range of how patients describe what they are feeling

Additionally, alterations in proteins involved in ER and ERGIC vesicles (e.g., TMED2, TMED9, TMED10, LMAN1, and LMAN2) suggest disruptions in protein trafficking and secretion

Specifically, this activation effect is mainly reflected in two aspects: it further activates the downstream mTOR molecules through the Akt-mTOR axis, directly promoting the synthesis of muscle proteins and inhibits the binding of the myostatin promoter, thereby reducing the expression of myostatin and ultimately alleviating muscle atrophy