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In May, Novo ousted its CEO of eight years, citing "recent market challenges" and "the development of the company's share price." Six months later, all independent members of the board stepped down due to a disagreement with Novo's controlling shareholder over the pace of change and discontent over how it had addressed challenges in the U.S

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The median (interquartile range) time to end of progression within 4 h of administration was 19.8 min (16.242.6) for attacks treated with 600 mg sebetralstat in KONFIDENT-S, which was similar to 19.8 min (16.897.2) and 19.2 min (16.846.2) for attacks treated with 300 mg and 600 mg sebetralstat in KONFIDENT