Does the type of GLP-1 (oral vs injectable) change the early dosing rules
Akt, serine threonine kinase
The most common side effects include nausea, constipation, bloating, reduced appetite, fatigue, and mild headaches
Diabetic Retinopathy: In individuals with diabetes, rapid improvements in blood sugar controlsometimes seen with GLP-1 drugscan exacerbate diabetic retinopathy, a condition that damages the blood vessels in the retina
GLP-1 modulates actin polymerization, improving insulin sensitivity and glucose-stimulated insulin secretion Chronic hyperglycemia, or glucotoxicity, causes pancreatic cell dysfunction, diminished glucose-stimulated insulin secretion, and the production of long actin stress fibers 6,7