HD is caused by an expanded CAG repeat in the huntingtin (HTT) gene, leading to the production of a mutant huntingtin protein with toxic gain-of-function properties
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Therefore, maintaining the right drug dosage to achieve adequate ROS levels may be essential for anti-tumor efficacy
D., Tama, E., Fansa, S., Ghusn, W., Anazco, D., Acosta, A., Faubion, S
2019: 6247169, doi: Bordoni L, Sawicka AK, Szarmach A, Winklewski PJ, Olek RA, Gabbianelli R