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These molecular interactions facilitate activation of the Ras/RAF/MEK/ERK pathway, quantifiable through phospho-specific antibody detection and real-time PCR analysis of immediate early gene expression profiles

They are not approved for human or veterinary use, and are intended solely for experimental or research purposes

Severe gastrointestinal symptoms could also lead to dehydration, which may increase the risk of methotrexate toxicity by affecting renal function

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To make this work without compromising, the Pimoroni crew has taken the liberty of making this board a tad longer than a standard Pico (OK, 24mm!) and used the RP2350B chip (the B stands for Big)