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Copper excess triggers oxidative stress (by impairing antioxidant enzymes and NO bioavailability) and disrupts Ca homeostasis, leading to endothelial dysfunction, cardiac hypertrophy, and contractile impairment

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However, it is important to talk to your healthcare provider about your medical history and any medical conditions you may have, as well as any medications you are currently taking

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The delivery methods also differ considerably - while injections provide controlled, consistent release of medication through subcutaneous administration, patches rely on unproven transdermal delivery that cannot effectively transport the hormone through the skin barrier