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In AD, along with amyloid and tau phosphorylation, there is an associated increase in inflammation/glial activation, a decrease in synaptic function, an increase in astrocyte activation, and a state of insulin resistance

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[DOI] [PubMed] [Google Scholar] 112.Jiang X., Liu S., Wang Y., Zhang R., Opoku Y.K., Xie Y., Li D., Ren G