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Stains for melanin or S100 to identify the melanocytic nature of the pigment-laden dendritic cells help make this distinction

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While GLP-1s can effectively promote weight loss when combined with diet and exercise, consumers should be aware of potential side effects and how to address these with a healthcare provider

This is not surprising, considering that tirzepatide and semaglutide evoked more pronounced TBWL and also have glucose-lowering effects by slowing gastric emptying, stimulating insulin secretion and inhibiting glucagon secretion in a glucose-dependent manner, independent of their effects on body weight 50,51

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