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15 Drug elimination by both hepatic metabolism and renal excretion is limited in neonates, so drug dosing intervals need to be increased for many drugs, such as aminoglycosides and nonsteroidal anti-inflammatory drugs.

Glutathione IV therapy is generally not recommended during pregnancy or breastfeeding due to insufficient safety data

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doi: 10.1016/S0190-9622(85)70188-0 11 LonnbergASSkovLSkyttheAKyvikKOPedersenOBThomsenSF

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