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Additionally, the lncRNA LIPE-AS1 is highly expressed in PCOS follicular fluid EVs and modulates steroid metabolism, granulosa cell proliferation, and apoptosis through the LIPE-AS1/miR-4306/LHCGR axis, contributing to poor oocyte quality and impaired embryo development (Yu et al., 2024)

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The Impact of GLP-1 on the Balance between Bone Formation and Bone Resorption Normal bone metabolism in humans involves both bone formation and bone resorption in a balanced state of equilibrium