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chronic liver disease and hepatitis may present with elevated levels Renal impairment : Reduced clearance can contribute to accumulation, though this is rarely clinically significant Solid tumours : Certain malignancies, particularly hepatocellular carcinoma and metastatic disease, may elevate B12 levels [3] Evidence suggests that unexplained markedly elevated B12 levels without supplementation may sometimes be associated with underlying disease

The FDA's Pharmacy Compounding Advisory Committee will meet on Wednesday and Thursday to consider if seven peptides should be added to the agency's 503A Bulks List, a step that would permit state-licensed compounding pharmacies to prepare the substances for patients with prescriptions

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