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For diabetes management, both oral and injectable GLP-1 medications effectively reduce hemoglobin A1c levels, though injectable forms typically show slightly greater reductions

Panel recommendations It is crucial to select an antidiabetic drug with established efficacy to address multiple pathophysiological defects

Research indicates therapeutic benefit typically emerges at 1.01.2 mg weekly

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Whole bone loss is influenced by initial body weight, age, sex, physical activity, extent of energy restriction, and rate of weight reduction, with older individuals and women experiencing greater bone loss [67]