These temperature-sensitive peptide medicationsincluding semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)require specific storage conditions to maintain therapeutic effectiveness
Overall, the most bothersome or severe symptoms reported by the patients (Figure 1) were decreased sexual interest (24%), fatigue (14%), insomnia (11%), pain during vaginal sex (10%), and general pain (10%)
Substantial Weight Reduction In a 48-week Phase 2 obesity trial, participants receiving retatrutide 12 mg once weekly reached an average 24.2% body weight reduction , with weight loss continuing through the study period rather than plateauing early
Administer WEGOVY in combination with a reduced-calorie diet and increased physical activity
See, e.g., FDA warning letter to Eurosirel S.P.A